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GENE - TERM ANNOTATION REPORT

RGD ID: 1586495
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl1
Name: C-C motif chemokine ligand 1
Acc ID: GO:0008009
Term: chemokine activity
Definition: The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
Definition Source(s): GOC:BHF, GOC:rl, PMID:12183377, Wikipedia:Chemokine
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl1enablesISOCCL1 (Homo sapiens)1624291RGD PMID:1557400

PMID:1557400
Ccl1enablesIBAMGI:104593 or MGI:1097153 or MGI:1099448 or MGI:1346316 or MGI:1349183 or MGI:98260 or PANTHER:PTN000245709 or Ccl6 (Rattus norvegicus) or Ccl11 (Rattus norvegicus) or Ccl2 (Rattus norvegicus) or Ccl20 (Rattus norvegicus) or Ccl3 (Rattus norvegicus) or Ccl4 (Rattus norvegicus) or Cx3cl1 (Rattus norvegicus) or Ccl5 (Rattus norvegicus) or UniProtKB:O00175 or UniProtKB:O00585 or UniProtKB:O15444 or UniProtKB:P10147 or UniProtKB:P13501 or UniProtKB:P22362 or UniProtKB:P47992 or UniProtKB:P51671 or UniProtKB:P55773 or UniProtKB:P78423 or UniProtKB:P80098 or UniProtKB:Q99616 or UniProtKB:Q99731 or UniProtKB:Q9Y258 or ZFIN:ZDB-GENE-110222-21600115GO_CentralGO_REF:0000033

GO_REF:0000033
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