GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | H3f4 | increases acetylation | ISO | H3-4 (Homo sapiens) | 6480464 | CTD | Valproic Acid results in increased acetylation of H3-4 protein | PMID:14576182 PMID:19030781 PMID:19924110 | H3f4 | increases acylation | ISO | H3f4 (Mus musculus) | 6480464 | CTD | Valproic Acid results in increased acylation of H3F4 protein | PMID:15737665 | H3f4 | increases methylation | ISO | H3-4 (Homo sapiens) | 6480464 | CTD | Valproic Acid results in increased methylation of H3-4 gene | PMID:29154799 | H3f4 | multiple interactions | ISO | H3-4 (Homo sapiens) | 6480464 | CTD | [Decitabine co-treated with Valproic Acid] results in decreased methylation of H3-4 protein; [Valproic Acid co-treated with Decitabine] results in increased acetylation of H3-4 protein | PMID:19030781 | | ||||||||||||||||||||||
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