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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1583832
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pgd
Name: phosphogluconate dehydrogenase
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pgddecreases activityISOPgd (Mus musculus)6480464CTDDiethylhexyl Phthalate results in decreased activity of PGD proteinPMID:31486570
Pgdmultiple interactionsISOPgd (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of PGD mRNAPMID:28433925
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