Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1566119
Species: Rattus norvegicus
RGD Object: Gene
Symbol: H2ax
Name: H2A.X variant histone
Acc ID: CHEBI:34292
Term: 1,3-benzothiazole-2-thiol
Definition: 1,3-Benzothiazole substituted at the 2-position with a sulfanyl group.
Chemical ID: MESH:C005563
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H2axincreases expressionISOH2AX (Homo sapiens)6480464CTDcaptax results in increased expression of H2AX proteinPMID:35279910
H2axmultiple interactionsISOH2AX (Homo sapiens)6480464CTD1-aminobenzotriazole inhibits the reaction [captax results in increased expression of H2AX protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [captax results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [captax results in increased expression of H2AX protein]; Disulfiram inhibits the reaction [captax results in increased expression of H2AX protein]PMID:35279910
Go Back to source page   Continue to Ontology report