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GENE - TERM ANNOTATION REPORT

RGD ID: 1565480
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ube2u
Name: ubiquitin conjugating enzyme E2 U
Acc ID: GO:0006281
Term: DNA repair
Definition: The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
Definition Source(s): PMID:11563486
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ube2uinvolved_inIBAFB:FBgn0004436 or PANTHER:PTN000630651 or SGD:S000003026 or UniProtKB:P49459 or UniProtKB:P63146 or WB:WBGene000067011600115GO_CentralGO_REF:0000033

GO_REF:0000033
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