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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1565451
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lonrf3
Name: LON peptidase N-terminal domain and ring finger 3
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lonrf3affects expressionISOLonrf3 (Mus musculus)6480464CTDValproic Acid affects the expression of LONRF3 mRNAPMID:17963808
Lonrf3decreases expressionISOLONRF3 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of LONRF3 mRNAPMID:29154799
Lonrf3increases expressionISOLONRF3 (Homo sapiens)6480464CTDValproic Acid results in increased expression of LONRF3 mRNAPMID:23179753 PMID:24935251 PMID:25192806 PMID:27188386 PMID:28001369
Lonrf3increases methylationISOLONRF3 (Homo sapiens)6480464CTDValproic Acid results in increased methylation of LONRF3 genePMID:29154799
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