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RGD ID: 1565122
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ttc21b
Name: tetratricopeptide repeat domain 21B
Acc ID: GO:0021702
Term: cerebellar Purkinje cell differentiation
Definition: The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.
Definition Source(s): GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jid, PMID:15157725
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ttc21bacts_upstream_of_or_withinISOTtc21b (Mus musculus)1624291RGDMGI:2137515 MGI:2152544 MGI:2179048 MGI:5587034 PMID:29615573

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