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GENE - TERM ANNOTATION REPORT

RGD ID: 1565122
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ttc21b
Name: tetratricopeptide repeat domain 21B
Acc ID: DOID:1184
Term: nephrotic syndrome
Definition: A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Nephrotic_syndrome "DO" "DO", https://www.niddk.nih.gov/health-information/kidney-disease/nephrotic-syndrome-adults "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ttc21b ISOTTC21B (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Nephrotic syndromePMID:18414213 PMID:21258341 PMID:24876116 PMID:25741868 PMID:26940125 PMID:28492532 PMID:29127259 PMID:32173348 PMID:33532864
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