GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1564611
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pnpla6
Name: patatin-like phospholipase domain containing 6
Acc ID: CHEBI:50095
Term: bucladesine
Definition: A 3',5'-cyclic purine nucleotide that is the 2'-butanoate ester and 6-N-butanoyl derivative of 3',5'-cyclic AMP.
Chemical ID: MESH:D003994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:16057016480464CTDBucladesine results in increased expression of PNPLA6 mRNA

PMID:20380879
multiple interactionsISORGD:16057016480464CTDBucladesine results in increased expression of and results in increased activity of PNPLA6 protein

Cycloheximide inhibits the reaction [Bucladesine results in increased activity of PNPLA6 protein]

PMID:20380879
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.