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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1564025
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eda2r
Name: ectodysplasin A2 receptor
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eda2rincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of EDA2R mRNAPMID:33387578
Eda2raffects expressionISOEda2r (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of EDA2R mRNAPMID:21570461 PMID:26377647 PMID:28922406
Eda2rmultiple interactionsISOEda2r (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to EDA2R promoter]PMID:19654925
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