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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1564025
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eda2r
Name: ectodysplasin A2 receptor
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eda2rincreases expressionEXP 6480464CTDAflatoxin B1 results in increased expression of EDA2R mRNAPMID:33354967
Eda2rdecreases methylationISOEDA2R (Homo sapiens)6480464CTDAflatoxin B1 results in decreased methylation of EDA2R gene; Aflatoxin B1 results in decreased methylation of EDA2R intronPMID:27153756 PMID:30157460
Eda2rincreases expressionISOEDA2R (Homo sapiens)6480464CTDAflatoxin B1 results in increased expression of EDA2R mRNAPMID:21632981
Eda2rincreases expressionISOEda2r (Mus musculus)6480464CTDAflatoxin B1 results in increased expression of EDA2R mRNAPMID:19770486
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