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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1563868
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tbl1x
Name: transducin (beta)-like 1 X-linked
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tbl1xaffects expressionISOTbl1x (Mus musculus)6480464CTDValproic Acid affects the expression of TBL1X mRNAPMID:17292431
Tbl1xdecreases expressionISOTBL1X (Homo sapiens)6480464CTDValproic Acid results in decreased expression of TBL1X mRNAPMID:24935251 PMID:26272509 PMID:28001369
Tbl1xincreases methylationISOTBL1X (Homo sapiens)6480464CTDValproic Acid results in increased methylation of TBL1X genePMID:29154799
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