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GENE - TERM ANNOTATION REPORT

RGD ID: 1563860
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rps6ka3
Name: ribosomal protein S6 kinase A3
Acc ID: DOID:9007454
Term: amyloidoma
Definition: This is a nodular localized form of amyloidosis with predominantly thoracic localization (pulmonary amyloidosis), considered as secondary protein structure disease in which insoluble protein fibrils accumulate extracellularly. The form of primary amyloid in amyloidoma is characterized by abnormal deposition of light chain proteins composed of monoclonal immunoglobulin. Pulmonary amyloidomas are rare and are often found incidentally as solitary or multiple calcified nodules and masses on chest radiographs in asymptomatic elderly patients.
Definition Source(s): NCI:C41137
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
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