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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1563841
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Irak1
Name: interleukin-1 receptor-associated kinase 1
Acc ID: CHEBI:17573
Term: glycyrrhetinate
Definition: A monocarboxylic acid anion that has formula C30H45O4.
Chemical ID: MESH:C119129
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Irak1multiple interactionsISOIrak1 (Mus musculus)6480464CTDGlycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] promotes the reaction [TRAF6 protein binds to IRAK1 protein]]PMID:28213090
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