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GENE - TERM ANNOTATION REPORT

RGD ID: 1562468
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aph1b
Name: aph-1 homolog B, gamma secretase subunit
Acc ID: GO:0034205
Term: amyloid-beta formation
Definition: The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP).
Definition Source(s): GOC:mah
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aph1bacts_upstream_of_or_withinISOAph1b (Mus musculus)1624291RGDMGI:1202717 MGI:1891700 PMID:16371134

PMID:16371134
Aph1binvolved_inISOAPH1B (Homo sapiens)1624291RGDUniProtKB:P05067 UniProtKB:P49768 PMID:12763021 PMID:27608597

PMID:12763021 PMID:27608597
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