Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1562269
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nod1
Name: nucleotide-binding oligomerization domain containing 1
Acc ID: CHEBI:2430
Term: aconitine
Definition: A diterpenoid that is 20-ethyl-3alpha,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitane-8,14alpha-diol having acetate and benzoate groups at the 8- and 14-positions respectively.
Chemical ID: MESH:D000157
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nod1increases expressionEXP 6480464CTDAconitine results in increased expression of NOD1 proteinPMID:33236894
Nod1multiple interactionsEXP 6480464CTDNOD1 protein affects the reaction [Aconitine results in increased expression of CASP1 protein]; NOD1 protein affects the reaction [Aconitine results in increased expression of IL18 protein]; NOD1 protein affects the reaction [Aconitine results in increased expression of IL1B protein]; NOD1 protein affects the reaction [Aconitine results in increased expression of NLRP3 protein]PMID:33236894
Go Back to source page   Continue to Ontology report