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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1562269
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nod1
Name: nucleotide-binding oligomerization domain containing 1
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nod1increases expressionISONOD1 (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of NOD1 mRNAPMID:23452621
Nod1multiple interactionsISONOD1 (Homo sapiens)6480464CTD3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency results in increased expression of NOD1 mRNA]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of NOD1 mRNA]; Genistein inhibits the reaction [Oxygen deficiency results in increased expression of NOD1 mRNA]; Plant Extracts inhibits the reaction [Oxygen deficiency results in increased expression of NOD1 mRNA]; resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of NOD1 mRNA]PMID:23452621
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