Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

GENE - TERM ANNOTATION REPORT

RGD ID: 1562253
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Wnt16
Name: Wnt family member 16
Acc ID: GO:0060070
Term: canonical Wnt signaling pathway
Definition: A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via beta-catenin, and end with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
Definition Source(s): PMID:11532397, PMID:19619488
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Wnt16involved_inIBAFB:FBgn0004360 or FB:FBgn0031902 or FB:FBgn0284084 or MGI:101948 or MGI:108061 or MGI:1197020 or MGI:1261834 or MGI:2446084 or MGI:98953 or MGI:98954 or MGI:98955 or MGI:98956 or MGI:98957 or MGI:98958 or MGI:98961 or MGI:98962 or PANTHER:PTN000246517 or Wnt7a (Rattus norvegicus) or UniProtKB:O00744 or UniProtKB:O00755 or UniProtKB:O14904 or UniProtKB:O14905 or UniProtKB:P04628 or UniProtKB:P09544 or UniProtKB:P56703 or UniProtKB:P56704 or UniProtKB:P56705 or UniProtKB:P56706 or UniProtKB:Q2LMP1 or UniProtKB:Q93097 or UniProtKB:Q93098 or UniProtKB:Q98SN7 or UniProtKB:Q9GZT5 or UniProtKB:Q9H1J5 or WB:WBGene00001188 or WB:WBGene00003395 or ZFIN:ZDB-GENE-980526-332 or ZFIN:ZDB-GENE-990415-2791600115GO_CentralGO_REF:0000033

GO_REF:0000033
Go Back to source page   Continue to Ontology report