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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1562112
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Foxp3
Name: forkhead box P3
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Foxp3decreases expressionISOFoxp3 (Mus musculus)6480464CTDEstradiol results in decreased expression of FOXP3 mRNAPMID:19693291
Foxp3multiple interactionsISOFOXP3 (Homo sapiens)6480464CTD[Progesterone co-treated with Estradiol] inhibits the reaction [Vaccines, Virus-Like Particle results in decreased expression of FOXP3 protein]; Estradiol inhibits the reaction [Vaccines, Virus-Like Particle results in decreased expression of FOXP3 protein]PMID:20130130
Foxp3multiple interactionsISOFoxp3 (Mus musculus)6480464CTD[Estradiol co-treated with Progesterone] results in decreased expression of FOXP3 mRNAPMID:19693291
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