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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1559690
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ddias
Name: DNA damage-induced apoptosis suppressor
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddiasdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of DDIAS mRNAPMID:25181051 PMID:34947998
Ddiasmultiple interactionsEXP 6480464CTD[bisphenol A co-treated with Testosterone] results in increased expression of DDIAS mRNAPMID:26496021
Ddiasdecreases expressionISODDIAS (Homo sapiens)6480464CTDbisphenol A results in decreased expression of DDIAS mRNAPMID:29275510
Ddiasdecreases methylationISODDIAS (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of DDIAS genePMID:31601247
Ddiasincreases methylationISODdias (Mus musculus)6480464CTDbisphenol A results in increased methylation of DDIAS promoterPMID:27312807
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