GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Med1 | increases localization | ISO | Med1 (Mus musculus) | 6480464 | CTD | Phenobarbital results in increased localization of MED1 protein | PMID:16109766 | Med1 | increases response to substance | ISO | Med1 (Mus musculus) | 6480464 | CTD | MED1 gene mutant form results in increased susceptibility to Phenobarbital | PMID:16109766 | Med1 | multiple interactions | ISO | Med1 (Mus musculus) | 6480464 | CTD | MED1 protein promotes the reaction [Phenobarbital results in increased expression of CYP1A2 mRNA]; MED1 protein promotes the reaction [Phenobarbital results in increased expression of CYP2B10 mRNA]; MED1 protein promotes the reaction [Phenobarbital results in increased expression of CYP3A11 mRNA]; MED1 protein promotes the reaction [Phenobarbital results in increased localization of and results in increased activity of NR1I3 protein] | PMID:16109766 | |
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