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GENE - TERM ANNOTATION REPORT

RGD ID: 1558622
Species: Mus musculus
RGD Object: Gene
Symbol: Dnah5
Name: dynein, axonemal, heavy chain 5
Acc ID: DOID:9001591
Term: Ciliary Motility Disorders
Definition: Conditions caused by abnormal CILIA movement in the body, usually causing KARTAGENER SYNDROME, chronic respiratory disorders, chronic SINUSITIS, and chronic OTITIS. Abnormal ciliary beating is likely due to defects in any of the 200 plus ciliary proteins, such as missing motor enzyme DYNEIN arms.
Definition Source(s): MESH:D002925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dnah5 ISODNAH5 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Ciliary dyskinesiaPMID:11062149 PMID:11788826 PMID:11912187 PMID:15750039 PMID:16199547 PMID:16492982 PMID:16627867 PMID:17534128 PMID:17576681 PMID:18492703 PMID:18950741 PMID:19357118 PMID:19630565 PMID:19763152 PMID:20301301 PMID:20307669 PMID:2127064 PMID:21270641 PMID:22406018 PMID:22416021 PMID:22499950 PMID:23261302 PMID:23477994 PMID:2389146 PMID:23891469 PMID:24033266 PMID:24150548 PMID:24448499 PMID:24498942 PMID:24905662 PMID:2506606 PMID:25066065 PMID:25118008 PMID:25186273 PMID:25326635 PMID:25525159 PMID:25640679 PMID:25741868 PMID:25802884 PMID:26139845 PMID:26228299 PMID:26373788 PMID:26918822 PMID:26938784 PMID:27428751 PMID:27618201 PMID:27637300 PMID:27637763 PMID:27779714 PMID:27988889 PMID:28492532 PMID:28939216 PMID:28976722 PMID:29089047 PMID:29363216 PMID:29402277 PMID:29453417 PMID:30067075 PMID:30148830 PMID:30290127 PMID:30293990 PMID:30300419 PMID:31213628 PMID:31443223 PMID:31469207 PMID:31589614 PMID:31624253 PMID:31638833 PMID:31765523 PMID:31772028 PMID:31879361 PMID:32111882 PMID:32357925 PMID:32367404 PMID:32502479 PMID:32502767 PMID:33574797 PMID:33577779 PMID:33589394 PMID:33635012 PMID:33715250 PMID:9536098
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