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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558311
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2b10
Name: cytochrome P450, family 2, subfamily b, polypeptide 10
Acc ID: CHEBI:34027
Term: 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
Definition: A diarylmethane that has formula C14H9Cl5.
Chemical ID: MESH:C016340
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2b10affects expressionEXP 6480464CTDo,p'-DDT affects the expression of CYP2B10 mRNAPMID:18925944
Cyp2b10increases expressionISOCYP2B6 (Homo sapiens)6480464CTDo,p'-DDT results in increased expression of CYP2B6 mRNA; o,p'-DDT results in increased expression of CYP2B6 proteinPMID:15548381 PMID:21924250
Cyp2b10multiple interactionsISOCYP2B6 (Homo sapiens)6480464CTDo,p'-DDT inhibits the reaction [Androstenols inhibits the reaction [NR1I3 protein results in increased expression of CYP2B6 mRNA]]PMID:10037683
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