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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558311
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2b10
Name: cytochrome P450, family 2, subfamily b, polypeptide 10
Acc ID: CHEBI:30614
Term: benzo[a]pyrene diol epoxide I
Definition: An epoxide that has formula C20H14O3.
Chemical ID: MESH:D015123
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2b10affects response to substanceISOCYP2B6 (Homo sapiens)6480464CTDCYP2B6 gene SNP affects the susceptibility to 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxidePMID:22521834
Cyp2b10increases expressionISOCYP2B6 (Homo sapiens)6480464CTD7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of CYP2B6 mRNAPMID:19150397
Cyp2b10multiple interactionsISOCYP2B6 (Homo sapiens)6480464CTDCYP2B6 gene SNP affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide binds to ALB protein]PMID:22521834
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