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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558284
Species: Mus musculus
RGD Object: Gene
Symbol: Ugt1a2
Name: UDP glucuronosyltransferase 1 family, polypeptide A2
Acc ID: CHEBI:66331
Term: xanthohumol
Definition: A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'. Isolated from Humulus lupulus, it induces apoptosis in human malignant glioblastoma cells.
Chemical ID: MESH:C104536
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugt1a2multiple interactionsISOUGT1A3 (Homo sapiens)6480464CTD[xanthohumol co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of UGT1A2 mRNAPMID:22138251
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