GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | H2ax | increases phosphorylation | EXP | | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein | PMID:22331492 | H2ax | multiple interactions | EXP | | 6480464 | CTD | POLH protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; POLK protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; POLL protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; REV1 protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]; REV3L protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein] | PMID:22331492 | H2ax | increases expression | ISO | H2AX (Homo sapiens) | 6480464 | CTD | 4-hydroxy-2-nonenal results in increased expression of H2AX protein | PMID:34503147 | H2ax | multiple interactions | ISO | H2AX (Homo sapiens) | 6480464 | CTD | [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin co-treated with 4-hydroxy-2-nonenal] results in increased expression of H2AX protein | PMID:34503147 | | ||||||||||||||||||||||
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