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RGD ID: 1557448
Species: Mus musculus
RGD Object: Gene
Symbol: Top2b
Name: topoisomerase (DNA) II beta
Acc ID: GO:0005634
Term: nucleus
Definition: A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
Definition Source(s): GOC:go_curators
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Top2b ISORGD:15861562290270RGD GO_REF:0000096, MGI:MGI:4417868
Top2b IBAPANTHER:PTN0000188882290270GO_Central (MGI:MGI:6201960, PMID:21873635)

MGI:MGI:6201960, PMID:21873635
Top2b IDA 2290270MGI (MGI:MGI:2158857, PMID:11835579), (MGI:MGI:895157, PMID:9224616)

MGI:MGI:2158857, MGI:MGI:895157, PMID:11835579, PMID:9224616
Top2b ISOUniProtKB:Q028802290270MGI GO_REF:0000096, MGI:MGI:4834177
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.