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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557204
Species: Mus musculus
RGD Object: Gene
Symbol: Ces2e
Name: carboxylesterase 2E
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDBenzo(a)pyrene results in increased expression of CES2E mRNA

PMID:19770486, PMID:21569818, PMID:21964900, PMID:22610609, PMID:23735875
multiple interactionsEXP 6480464CTD[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CES2E mRNA

PMID:27858113
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.