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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553791
Species: Mus musculus
RGD Object: Gene
Symbol: Ugt2b1
Name: UDP glucuronosyltransferase 2 family, polypeptide B1
Acc ID: CHEBI:41879
Term: dexamethasone
Definition: A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.
Chemical ID: MESH:D003907
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ugt2b1affects expressionISOUgt2b1 (Rattus norvegicus)6480464CTDDexamethasone affects the expression of UGT2B1 mRNAPMID:15102944
Ugt2b1increases expressionISOUgt2b1 (Rattus norvegicus)6480464CTDDexamethasone results in increased expression of UGT2B1 mRNA; Dexamethasone results in increased expression of UGT2B17 mRNAPMID:11328961 PMID:15102944 PMID:20832446 PMID:21146967
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