GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Havcr1 | increases expression | ISO | Havcr1 (Rattus norvegicus) | 6480464 | CTD | Doxorubicin results in increased expression of HAVCR1 mRNA; Doxorubicin results in increased expression of HAVCR1 protein | PMID:19225054 PMID:31376360 PMID:35987278 | Havcr1 | increases secretion | ISO | Havcr1 (Rattus norvegicus) | 6480464 | CTD | Doxorubicin results in increased secretion of HAVCR1 protein | PMID:28885000 | Havcr1 | multiple interactions | ISO | Havcr1 (Rattus norvegicus) | 6480464 | CTD | Angiotensin II Type 1 Receptor Blockers inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 mRNA]; Angiotensin II Type 1 Receptor Blockers inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 protein]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 mRNA]; Lisinopril inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 protein]; Nicorandil inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 protein]; Tannic Acid inhibits the reaction [Doxorubicin results in increased expression of HAVCR1 mRNA] | PMID:19225054 PMID:31376360 PMID:35987278 | |
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