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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553302
Species: Mus musculus
RGD Object: Gene
Symbol: Gnrh1
Name: gonadotropin releasing hormone 1
Acc ID: CHEBI:34205
Term: 2,2',4,5-tetrachlorobiphenyl
Definition: A tetrachlorobiphenyl that is biphenyl in which the hydrogens at positions 2, 4, 5, and 2' are replaced by chlorines.
Chemical ID: MESH:C042128
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gnrh1affects expressionEXP 6480464CTD2,4,4',5-tetrachlorobiphenyl affects the expression of GNRH1 proteinPMID:19362103
Gnrh1multiple interactionsEXP 6480464CTD[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with 2,4,4',5-tetrachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] affects the expression of GNRH1 protein; fulvestrant affects the reaction [2,4,4',5-tetrachlorobiphenyl affects the expression of GNRH1 protein]PMID:19362103
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