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GENE - TERM ANNOTATION REPORT

RGD ID: 1552857
Species: Mus musculus
RGD Object: Gene
Symbol: Abca7
Name: ATP-binding cassette, sub-family A member 7
Acc ID: GO:0042626
Term: ATPase-coupled transmembrane transporter activity
Definition: Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.
Definition Source(s): GOC:mtg_transport, ISBN:0815340729
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abca7enablesIBAPANTHER:PTN000442469 or Abca1 (Rattus norvegicus) or UniProtKB:O94911 or UniProtKB:Q997582290270GO_Central GO_REF:0000033
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