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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552819
Species: Mus musculus
RGD Object: Gene
Symbol: Aurka
Name: aurora kinase A
Acc ID: CHEBI:27563
Term: arsenic atom
Definition: A pnictogen that has formula As.
Chemical ID: MESH:D001151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aurkaincreases expressionISOAURKA (Homo sapiens)6480464CTDArsenic results in increased expression of AURKA mRNA; Arsenic results in increased expression of AURKA proteinPMID:23174854
Aurkamultiple interactionsISOAURKA (Homo sapiens)6480464CTD[Arsenic co-treated with Estradiol] results in increased expression of AURKA mRNA; Arsenic results in increased phosphorylation of and results in increased activity of AURKA protein; E2F1 protein affects the reaction [Arsenic results in increased expression of AURKA protein]PMID:23174854 PMID:33047385
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