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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552629
Species: Mus musculus
RGD Object: Gene
Symbol: Nr1i3
Name: nuclear receptor subfamily 1, group I, member 3
Acc ID: CHEBI:34224
Term: 2,3,5,6-tetrachlorobiphenyl
Definition: A tetrachlorobiphenyl that is biphenyl in which one of the phenyl groups is substituted by chlorines at positions 2, 3, 5, and 6.
Chemical ID: MESH:C078132
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i3increases activityISONR1I3 (Homo sapiens)6480464CTD2,3,5,6-tetrachlorobiphenyl analog results in increased activity of NR1I3 protein; 2,3,5,6-tetrachlorobiphenyl results in increased activity of NR1I3 proteinPMID:26231822
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