GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nr1i3 | multiple interactions | EXP | | 6480464 | CTD | [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein | PMID:25835148 | Nr1i3 | increases expression | ISO | NR1I3 (Homo sapiens) | 6480464 | CTD | Rifampin results in increased expression of NR1I3 mRNA; Rifampin results in increased expression of NR1I3 protein | PMID:22733800 | Nr1i3 | increases expression | ISO | Nr1i3 (Rattus norvegicus) | 6480464 | CTD | Rifampin results in increased expression of NR1I3 mRNA | PMID:19118567 | Nr1i3 | multiple interactions | ISO | NR1I3 (Homo sapiens) | 6480464 | CTD | [NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I3 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I3 protein | PMID:22733800 PMID:25835148 | | ||||||||||||||||||||||
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