Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552455
Species: Mus musculus
RGD Object: Gene
Symbol: Fas
Name: Fas cell surface death receptor
Acc ID: CHEBI:5847
Term: ICI D1694
Definition: A N-acyl-amino acid that has formula C21H22N4O6S.
Chemical ID: MESH:C068874
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fasincreases expressionISOFAS (Homo sapiens)6480464CTDraltitrexed results in increased expression of FAS mRNA; raltitrexed results in increased expression of FAS proteinPMID:15161716 PMID:16204068
Fasmultiple interactionsISOFAS (Homo sapiens)6480464CTDraltitrexed results in increased expression of and results in increased localization of FAS protein; STAT1 protein promotes the reaction [raltitrexed results in increased localization of FAS protein]; TP53 protein affects the reaction [raltitrexed results in increased expression of FAS protein]; TYMS protein inhibits the reaction [raltitrexed results in increased expression of FAS protein]PMID:15161716 PMID:16204068
Go Back to source page   Continue to Ontology report