GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fas | multiple interactions | ISO | FAS (Homo sapiens) | 6480464 | CTD | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of FAS mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of FAS mRNA; Acrolein inhibits the reaction [FAS protein results in increased activity of CASP8 protein]; Acrolein inhibits the reaction [FAS protein results in increased cleavage of CASP8 protein] | PMID:17222828 PMID:32699268 | | ||||||||||||||||||||||
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