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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552173
Species: Mus musculus
RGD Object: Gene
Symbol: Acat2
Name: acetyl-Coenzyme A acetyltransferase 2
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acat2affects expressionEXP 6480464CTDValproic Acid affects the expression of ACAT2 mRNAPMID:17292431
Acat2affects expressionISOACAT2 (Homo sapiens)6480464CTDValproic Acid affects the expression of ACAT2 mRNAPMID:25979313
Acat2decreases expressionISOACAT2 (Homo sapiens)6480464CTDValproic Acid results in decreased expression of ACAT2 mRNAPMID:19101580 PMID:23179753 PMID:27188386 PMID:28001369 PMID:29154799
Acat2increases expressionISOAcat2 (Rattus norvegicus)6480464CTDValproic Acid results in increased expression of ACAT2 mRNAPMID:23665938
Acat2multiple interactionsISOACAT2 (Homo sapiens)6480464CTD[Hydralazine co-treated with Valproic Acid] results in increased expression of ACAT2 mRNAPMID:17183730
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