GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Adipoq | decreases expression | EXP | | 6480464 | CTD | GW 6471 results in decreased expression of ADIPOQ mRNA | PMID:21324916 | Adipoq | multiple interactions | EXP | | 6480464 | CTD | GW 6471 inhibits the reaction [[GW 7647 co-treated with PPARA protein] results in increased expression of ADIPOQ mRNA]; GW 6471 inhibits the reaction [ADIPOQ protein inhibits the reaction [Iron-Dextran Complex results in increased activity of CASP3 protein]]; GW 6471 inhibits the reaction [ADIPOQ protein promotes the reaction [[PPARA protein binds to HMOX1 promoter] which results in increased expression of HMOX1 mRNA]]; GW 6471 inhibits the reaction [ADIPOQ protein results in increased expression of and results in increased activity of HMOX1 protein]; GW 6471 inhibits the reaction [ADIPOQ protein results in increased expression of BCL2L1 protein] | PMID:20709802 PMID:21324916 | |
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