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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552054
Species: Mus musculus
RGD Object: Gene
Symbol: Adipoq
Name: adiponectin, C1Q and collagen domain containing
Acc ID: CHEBI:47612
Term: bezafibrate
Definition: A monocarboxylic acid amide obtained by the formal condensation of the carboxy group of 4-chlorobenzoic acid with the amino group of 2-[4-(2-aminoethyl)phenoxy]-2-methylpropanoic acid. Benafibrate is used for the treatment of hyperlipidaemia.
Chemical ID: MESH:D001629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adipoqincreases expressionEXP 6480464CTDBezafibrate results in increased expression of ADIPOQ mRNA; Bezafibrate results in increased expression of ADIPOQ proteinPMID:16574099 PMID:17190905 PMID:18513333 PMID:21324916
Adipoqincreases secretionEXP 6480464CTDBezafibrate results in increased secretion of ADIPOQ proteinPMID:17190905
Adipoqmultiple interactionsEXP 6480464CTDBezafibrate inhibits the reaction [Sodium Glutamate results in decreased expression of ADIPOQ protein]PMID:21549692
Adipoqincreases expressionISOADIPOQ (Homo sapiens)6480464CTDBezafibrate results in increased expression of ADIPOQ proteinPMID:21411093
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