GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Parp1 | decreases activity | EXP | | 6480464 | CTD | 3-aminobenzamide results in decreased activity of PARP1 protein | PMID:27026705 | Parp1 | multiple interactions | EXP | | 6480464 | CTD | 3-aminobenzamide inhibits the reaction [PARP1 protein results in increased susceptibility to Acetaminophen] | PMID:15601672 | Parp1 | decreases activity | ISO | PARP1 (Homo sapiens) | 6480464 | CTD | 3-aminobenzamide results in decreased activity of PARP1 protein | PMID:15075382 PMID:15670817 PMID:17669606 PMID:19056730 PMID:20493934 PMID:21370912 PMID:21399878 PMID:27026705 PMID:27233451 | Parp1 | decreases activity | ISO | Parp1 (Rattus norvegicus) | 6480464 | CTD | 3-aminobenzamide results in decreased activity of PARP1 protein | PMID:18815186 | Parp1 | multiple interactions | ISO | PARP1 (Homo sapiens) | 6480464 | CTD | 3-aminobenzamide inhibits the reaction [Asbestos, Amosite results in increased activity of PARP1 protein]; 3-aminobenzamide inhibits the reaction [Asbestos, Crocidolite results in increased activity of PARP1 protein]; 3-aminobenzamide inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]; 3-aminobenzamide inhibits the reaction [Capsaicin results in increased ADP-ribosylation of PARP1 protein modified form]; 3-aminobenzamide inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]; 3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of PARP1 protein]; 3-aminobenzamide inhibits the reaction [Lithocholic Acid analog results in increased activity of PARP1 protein]; 3-aminobenzamide inhibits the reaction [mezerein results in increased activity of PARP1 protein]; 3-aminobenzamide inhibits the reaction [PARP1 protein results in increased susceptibility to [Potassium Dichromate co-treated with nickel sulfate]]; 3-aminobenzamide inhibits the reaction [Smoke analog results in increased activity of PARP1 protein]; 3-aminobenzamide inhibits the reaction [sodium arsenite results in decreased expression of PARP1 protein]; 3-aminobenzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; 3-aminobenzamide promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]; 3-aminobenzamide promotes the reaction [Capsaicin results in increased expression of PARP1 protein]; [3-aminobenzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]; [3-aminobenzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]; [3-aminobenzamide results in decreased activity of PARP1 protein] which results in increased susceptibility to Cisplatin | PMID:11217149 PMID:17669606 PMID:20493934 PMID:2120135 PMID:2126186 PMID:21399878 PMID:21543585 PMID:22226932 PMID:26047893 PMID:36958258 | Parp1 | multiple interactions | ISO | Parp1 (Rattus norvegicus) | 6480464 | CTD | 3-aminobenzamide inhibits the reaction [[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in increased cleavage of PARP1 protein]; 3-aminobenzamide inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein] | PMID:28283887 | | ||||||||||||||||||||||
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