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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551333
Species: Mus musculus
RGD Object: Gene
Symbol: Hpcal1
Name: hippocalcin-like 1
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hpcal1multiple interactionsISOHpcal1 (Rattus norvegicus)6480464CTD[[Testosterone co-treated with Estradiol] affects the reaction [estradiol-17 beta-benzoate results in increased methylation of HPCAL1 promoter]] which affects the expression of HPCAL1 protein; [[Testosterone co-treated with Estradiol] results in increased methylation of HPCAL1 promoter] which results in decreased expression of HPCAL1 mRNA; [Testosterone co-treated with Estradiol] affects the reaction [estradiol-17 beta-benzoate results in increased methylation of HPCAL1 promoter]; [Testosterone co-treated with Estradiol] results in increased methylation of HPCAL1 promoterPMID:22109888
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