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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551095
Species: Mus musculus
RGD Object: Gene
Symbol: Rela
Name: v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Acc ID: CHEBI:28619
Term: acrylamide
Definition: A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia.
Chemical ID: MESH:D020106
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relaincreases expressionEXP 6480464CTDAcrylamide results in increased expression of RELA proteinPMID:27836571
Relaincreases expressionISORELA (Homo sapiens)6480464CTDAcrylamide results in increased expression of RELA proteinPMID:24508477
Relaincreases expressionISORela (Rattus norvegicus)6480464CTDAcrylamide results in increased expression of RELA mRNAPMID:28959563 PMID:29913234
Relamultiple interactionsISORELA (Homo sapiens)6480464CTDCurcumin inhibits the reaction [Acrylamide results in increased expression of RELA protein]; epigallocatechin gallate inhibits the reaction [Acrylamide results in increased expression of RELA protein]PMID:24508477
Relamultiple interactionsISORela (Rattus norvegicus)6480464CTD3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Acrylamide results in increased expression of RELA protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Acrylamide results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of and affects the localization of RELA protein]; Acrylamide results in increased expression of and affects the localization of RELA protein; boric acid inhibits the reaction [Acrylamide results in increased expression of RELA mRNA]; NFE2L2 protein promotes the reaction [Acrylamide results in increased expression of RELA protein]; pyrazolanthrone inhibits the reaction [Acrylamide results in increased expression of RELA protein]; U 0126 inhibits the reaction [Acrylamide results in increased expression of RELA protein]PMID:29426002 PMID:29913234
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