GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | multiple interactions | EXP | | 6480464 | CTD | [Copper co-treated with Lead co-treated with Cadmium co-treated with Zinc co-treated with Mercury co-treated with Chromium co-treated with Manganese co-treated with Nickel] results in increased expression of RELA protein | PMID:28035397 | Rela | affects localization | ISO | Rela (Rattus norvegicus) | 6480464 | CTD | Manganese affects the localization of RELA protein | PMID:22645130 | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | [manganese chloride results in increased abundance of Manganese] which affects the localization of RELA protein; Acetylcysteine affects the reaction [[manganese chloride results in increased abundance of Manganese] which affects the localization of RELA protein]; alpha-Tocopherol affects the reaction [[manganese chloride results in increased abundance of Manganese] which affects the localization of RELA protein]; IkK-16 compound affects the reaction [[manganese chloride results in increased abundance of Manganese] which affects the localization of RELA protein] | PMID:34310962 | Rela | multiple interactions | ISO | Rela (Rattus norvegicus) | 6480464 | CTD | 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone inhibits the reaction [Manganese affects the localization of RELA protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of RELA protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of RELA protein]; Manganese promotes the reaction [RELA protein binds to HDAC1 protein]; Manganese promotes the reaction [YY1 protein binds to RELA protein] | PMID:22645130 PMID:24469401 PMID:33314588 | | ||||||||||||||||||||||
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