GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Map1lc3b | increases expression | EXP | | 6480464 | CTD | bafilomycin A1 results in increased expression of MAP1LC3B protein modified form | PMID:31310755 | Map1lc3b | increases lipidation | EXP | | 6480464 | CTD | bafilomycin A1 results in increased lipidation of MAP1LC3B protein | PMID:30209975 | Map1lc3b | multiple interactions | EXP | | 6480464 | CTD | [bafilomycin A1 co-treated with Swainsonine] results in increased expression of MAP1LC3B mRNA; [bafilomycin A1 co-treated with Swainsonine] results in increased lipidation of MAP1LC3B protein; bafilomycin A1 promotes the reaction [tricalcium phosphate results in increased expression of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Triiodothyronine results in increased lipidation of MAP1LC3B protein]; Triiodothyronine promotes the reaction [bafilomycin A1 results in increased lipidation of MAP1LC3B protein] | PMID:30209975 PMID:36402259 PMID:37678662 | Map1lc3b | decreases degradation | ISO | Map1lc3b (Rattus norvegicus) | 6480464 | CTD | bafilomycin A1 results in decreased degradation of MAP1LC3B protein modified form | PMID:26459185 | Map1lc3b | increases cleavage | ISO | MAP1LC3B (Homo sapiens) | 6480464 | CTD | bafilomycin A1 results in increased cleavage of MAP1LC3B protein | PMID:29248574 | Map1lc3b | increases expression | ISO | MAP1LC3B (Homo sapiens) | 6480464 | CTD | bafilomycin A1 results in increased expression of MAP1LC3B protein; bafilomycin A1 results in increased expression of MAP1LC3B protein alternative form; bafilomycin A1 results in increased expression of MAP1LC3B protein modified form | PMID:24145604 PMID:25301941 PMID:29524503 PMID:34580807 | Map1lc3b | increases expression | ISO | Map1lc3b (Rattus norvegicus) | 6480464 | CTD | bafilomycin A1 results in increased expression of MAP1LC3B protein modified form | PMID:32278738 | Map1lc3b | increases lipidation | ISO | MAP1LC3B (Homo sapiens) | 6480464 | CTD | bafilomycin A1 results in increased lipidation of MAP1LC3B protein | PMID:33124469 PMID:35149085 PMID:35472370 PMID:38000454 | Map1lc3b | increases lipidation | ISO | Map1lc3b (Rattus norvegicus) | 6480464 | CTD | bafilomycin A1 results in increased lipidation of MAP1LC3B protein | PMID:32525084 | Map1lc3b | multiple interactions | ISO | MAP1LC3B (Homo sapiens) | 6480464 | CTD | [bafilomycin A1 co-treated with Miconazole] results in increased expression of MAP1LC3B protein; [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone co-treated with bafilomycin A1] results in increased expression of MAP1LC3B mRNA; [TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]]; ATG5 protein affects the reaction [bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]]; bafilomycin A1 affects the reaction [Ammonium Chloride results in increased metabolism of MAP1LC3B protein]; bafilomycin A1 affects the reaction [AZD4547 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 affects the reaction [AZD8186 affects the expression of MAP1LC3B protein modified form]; bafilomycin A1 inhibits the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [[alpha-Chlorohydrin co-treated with Diosgenin] results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [capivasertib results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [Curcumin results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [ginsenoside Rg2 results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [gossypol acetic acid results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [metarrestin results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 promotes the reaction [Miconazole results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [ovatodiolide results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Particulate Matter results in increased expression of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [Resveratrol results in increased expression of MAP1LC3B protein alternative form]; bafilomycin A1 promotes the reaction [Sevoflurane results in increased lipidation of MAP1LC3B protein]; bafilomycin A1 promotes the reaction [vistusertib results in increased expression of MAP1LC3B protein modified form]; bafilomycin A1 results in increased expression of and results in increased lipidation of MAP1LC3B protein; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]; Resveratrol promotes the reaction [[TNF protein co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein alternative form] | PMID:23880069 PMID:24145604 PMID:25301941 PMID:26853465 PMID:27305347 PMID:29908302 PMID:29938581 PMID:32981224 PMID:34634291 PMID:35149085 PMID:35472370 PMID:35872226 PMID:36070022 PMID:38000454 | Map1lc3b | multiple interactions | ISO | Map1lc3b (Rattus norvegicus) | 6480464 | CTD | [Doxorubicin co-treated with bafilomycin A1] results in increased expression of MAP1LC3B protein; [Glycyrrhizic Acid co-treated with bafilomycin A1] results in increased lipidation of MAP1LC3B protein; bafilomycin A1 inhibits the reaction [olaparib inhibits the reaction [Hydrogen Peroxide results in increased lipidation of MAP1LC3B protein]]; bafilomycin A1 promotes the reaction [C1QTNF9 protein results in increased expression of MAP1LC3B protein modified form] | PMID:32278738 PMID:32525084 PMID:36639873 | | ||||||||||||||||||||||
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