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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551009
Species: Mus musculus
RGD Object: Gene
Symbol: Map1lc3b
Name: microtubule-associated protein 1 light chain 3 beta
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map1lc3bdecreases expressionISOMap1lc3b (Rattus norvegicus)6480464CTDGlucose results in decreased expression of MAP1LC3B proteinPMID:29128638
Map1lc3bdecreases lipidationISOMap1lc3b (Rattus norvegicus)6480464CTDGlucose results in decreased lipidation of MAP1LC3B proteinPMID:35243728
Map1lc3bincreases expressionISOMAP1LC3B (Homo sapiens)6480464CTDGlucose deficiency results in increased expression of MAP1LC3B protein; Glucose deficiency results in increased expression of MAP1LC3B protein modified formPMID:34580807
Map1lc3bmultiple interactionsISOMAP1LC3B (Homo sapiens)6480464CTDU 0126 inhibits the reaction [Glucose deficiency results in increased expression of MAP1LC3B protein modified form]PMID:34580807
Map1lc3bmultiple interactionsISOMap1lc3b (Rattus norvegicus)6480464CTD3-methyladenine inhibits the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of MAP1LC3B protein]]; Inositol inhibits the reaction [Glucose results in decreased lipidation of MAP1LC3B protein]; N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of MAP1LC3B protein]; Sirolimus promotes the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of MAP1LC3B protein]]; ULK1 protein affects the reaction [Glucose results in decreased expression of MAP1LC3B protein]; ULK1 protein affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of MAP1LC3B protein]]PMID:29128638 PMID:35243728
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