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GENE - TERM ANNOTATION REPORT

RGD ID: 1551003
Species: Mus musculus
RGD Object: Gene
Symbol: Tlr2
Name: toll-like receptor 2
Acc ID: DOID:4677
Term: keratitis
Definition: A corneal disease that is characterized by inflammation of the cornea. (DO)
Definition Source(s): http://www.mayoclinic.org/diseases-conditions/keratitis/basics/definition/con-20035288 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tlr2 IMP 7794840RGDassociated with Onchocerciasis, Ocular; 
Tlr2 ISOTLR2 (Homo sapiens)8552914RGDassociated with Eye Infections, Fungal;mRNA,protein:increased expression:cornea: 
Tlr2treatmentISOTlr2 (Rattus norvegicus)8552816RGDassociated with Aspergillosis: 
Tlr2 ISOTLR2 (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:23661603
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