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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550949
Species: Mus musculus
RGD Object: Gene
Symbol: Hif1an
Name: hypoxia-inducible factor 1, alpha subunit inhibitor
Acc ID: CHEBI:35696
Term: cobalt dichloride
Definition: A cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is chloride. It is used as an indicator for water in desiccants.
Chemical ID: MESH:C018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hif1andecreases expressionISOHIF1AN (Homo sapiens)6480464CTDcobaltous chloride results in decreased expression of HIF1AN mRNA; cobaltous chloride results in decreased expression of HIF1AN proteinPMID:15695372 PMID:16705796 PMID:26174737
Hif1anmultiple interactionsISOHIF1AN (Homo sapiens)6480464CTDtetraethylenepentamine inhibits the reaction [cobaltous chloride results in decreased expression of HIF1AN protein]PMID:26174737
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