GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Phlpp1 | decreases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of PHLPP mRNA | PMID:19770486 PMID:22228805 | Phlpp1 | decreases methylation | EXP | | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of PHLPP1 exon; Benzo(a)pyrene results in decreased methylation of PHLPP1 intron | PMID:27901495 | Phlpp1 | multiple interactions | EXP | | 6480464 | CTD | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of PHLPP1 mRNA; AHR protein affects the reaction [Benzo(a)pyrene affects the expression of PHLPP mRNA] | PMID:22228805 PMID:27858113 | Phlpp1 | decreases expression | ISO | PHLPP1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of PHLPP mRNA; Benzo(a)pyrene results in decreased expression of PHLPP1 mRNA | PMID:20064835 PMID:20106945 PMID:21632981 PMID:32234424 | Phlpp1 | decreases methylation | ISO | PHLPP1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in decreased methylation of PHLPP1 5' UTR | PMID:27901495 | |
Go Back to source page | Continue to Ontology report |