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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550861
Species: Mus musculus
RGD Object: Gene
Symbol: Plg
Name: plasminogen
Acc ID: CHEBI:30185
Term: zinc(0)
Definition: An elemental zinc that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plgincreases expressionEXP 6480464CTDZinc results in increased expression of PLG mRNA; Zinc results in increased expression of PLG proteinPMID:21615740
Plgmultiple interactionsEXP 6480464CTD4-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid inhibits the reaction [Zinc results in increased expression of PLG mRNA]; 4-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid inhibits the reaction [Zinc results in increased expression of PLG protein]; 4-aminophenylmercuriacetate inhibits the reaction [Zinc results in increased expression of PLG mRNA]; 4-aminophenylmercuriacetate inhibits the reaction [Zinc results in increased expression of PLG protein]; BDNF protein affects the reaction [Zinc results in increased expression of PLG mRNA]; BDNF protein affects the reaction [Zinc results in increased expression of PLG protein]; Edetic Acid inhibits the reaction [Zinc results in increased expression of PLG mRNA]; Edetic Acid inhibits the reaction [Zinc results in increased expression of PLG protein]; Go 6976 inhibits the reaction [Zinc results in increased expression of PLG mRNA]; Go 6976 inhibits the reaction [Zinc results in increased expression of PLG protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Zinc results in increased expression of PLG mRNA]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Zinc results in increased expression of PLG protein]; staurosporine aglycone inhibits the reaction [Zinc results in increased expression of PLG mRNA]; staurosporine aglycone inhibits the reaction [Zinc results in increased expression of PLG protein]PMID:21615740
Plgaffects bindingISOPLG (Homo sapiens)6480464CTDPLG protein binds to ZincPMID:23896426
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